CARDIOMARKERS IN THE FIRST HOURS OF ACUTE MYOCARDIAL INFARCTION
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Abstract
In recent years, the definition of the components of the troponin complex of cardiomyocytes — troponin T and I - has been widely used in clinical practice. Their high specificity attracted the attention of cardiologists to them and in many ways changed the principles of modern diagnosis of MI. The myocardial protein troponin I (ThI) is found only in cardiomyocytes, it is not present in striated and smooth muscles.
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In order to diagnose AMI, clinical indicators must be combined with the content of biomarkers and ECG data. Of the enzymes, troponin and myoglobin have the greatest cardio specificity. ThI and myoglobin in AMI showed higher sensitivity compared to transaminase. The sensitivity of both ThI and myoglobin in AMI with a Q wave is the same. In AMI without the Q wave, myoglobin was more sensitive.